Hormonal regulation of longevity in mammals
نویسندگان
چکیده
منابع مشابه
Hormonal regulation of the epithelial Na+ channel: from amphibians to mammals.
High-resistance epithelia derived from amphibian sources such as frog skin, toad urinary bladder, and the A6 Xenopus laevis kidney cell line have been widely used to elucidate the underlying mechanisms involved in the regulation of vectorial ion transport. More recently, the isolation of high-resistance mammalian cell lines has provided model systems in which to study differences and similariti...
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Life-history theory predicts that reduced extrinsic risk of mortality should increase species longevity over evolutionary time. Increasing group size should reduce an individual's risk of predation, and consequently reduce its extrinsic risk of mortality. Therefore, we should expect a relationship between group size and maximum longevity across species, while controlling for well-known correlat...
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Hosts and parasites co-evolve, with each lineage exerting selective pressures on the other. Thus, parasites may influence host life-history characteristics, such as longevity, and simultaneously host life-history may influence parasite diversity. If parasite burden causes increased mortality, we expect a negative association between host longevity and parasite species richness. Alternatively, i...
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Methionine residues in proteins react readily with reactive oxygen species making them particularly sensitive to oxidation. However, because oxidized methionine can be reduced back in a catalyzed reaction, it has been suggested that methionine residues act as oxidant scavengers, protecting not only the proteins where they are located but also the surrounding macromolecules. To investigate wheth...
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I respond to Williams and Shattuck’s comments regarding the importance of eusociality on the longevity of fossorial species [1]. Williams and Shattuck extend our analysis [2] by compiling further data on fossorial and terrestrial mammals (less than 60 kg) and including eusociality as an additional factor in their analyses. They find that both eusociality and fossoriality are associated with inc...
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ژورنال
عنوان ژورنال: Ageing Research Reviews
سال: 2007
ISSN: 1568-1637
DOI: 10.1016/j.arr.2007.02.005